Home

Wiederholung Abgrund Affe hct116 p53 ko puma ko cells Barry Bluse Münze

Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent  Suppression of Oxidative Phosphorylation
Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation

p300 regulates p53-dependent apoptosis after DNA damage in colorectal  cancer cells by modulation of PUMA/p21 levels | PNAS
p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels | PNAS

Frontiers | p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a  Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells |  Oncology
Frontiers | p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells | Oncology

A, p53-KO HCT116 cells were incubated with aciculatin (5–10 µM) for 48... |  Download Scientific Diagram
A, p53-KO HCT116 cells were incubated with aciculatin (5–10 µM) for 48... | Download Scientific Diagram

FLIP(L) determines p53 induced life or death | bioRxiv
FLIP(L) determines p53 induced life or death | bioRxiv

Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells
Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells

The nuclear function of p53 is required for PUMA-mediated apoptosis induced  by DNA damage
The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage

Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* -  Journal of Biological Chemistry
Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry

PUMA is directly activated by NF-κB and contributes to TNF-α-induced  apoptosis | Cell Death & Differentiation
PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis | Cell Death & Differentiation

BITC treatment causes G2/M phase cell cycle arrest in PUMA knockout HCT-116  cells.
BITC treatment causes G2/M phase cell cycle arrest in PUMA knockout HCT-116 cells.

HCT116 p53+/+ and its isogenic knockout (p53−/−, PUMA−/−, Bax−/−,... |  Download Scientific Diagram
HCT116 p53+/+ and its isogenic knockout (p53−/−, PUMA−/−, Bax−/−,... | Download Scientific Diagram

PUMA is directly activated by NF-κB and contributes to TNF-α-induced  apoptosis | Cell Death & Differentiation
PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis | Cell Death & Differentiation

The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced  by DNA Damage
The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced by DNA Damage

Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER  stress-induced p53-independent PUMA expression
Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression

Figures and data in Prosurvival long noncoding RNA PINCR regulates a subset  of p53 targets in human colorectal cancer cells by binding to Matrin 3 |  eLife
Figures and data in Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 | eLife

PUMA-mediated copanlisib-induced apoptosis. A WT and PUMA-KO HCT116... |  Download Scientific Diagram
PUMA-mediated copanlisib-induced apoptosis. A WT and PUMA-KO HCT116... | Download Scientific Diagram

MicroRNA-203 induces apoptosis by upregulating Puma expression in colon and  lung cancer cells
MicroRNA-203 induces apoptosis by upregulating Puma expression in colon and lung cancer cells

Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and  NF-κB to suppress tumor cell growth | Oncogene
Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth | Oncogene

PUMA induction by crizotinib is largely dependent on p53. A, HCT116... |  Download Scientific Diagram
PUMA induction by crizotinib is largely dependent on p53. A, HCT116... | Download Scientific Diagram

Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* -  Journal of Biological Chemistry
Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry

PUMA Dissociates Bax and Bcl-XL to Induce Apoptosis in Colon Cancer Cells*  - Journal of Biological Chemistry
PUMA Dissociates Bax and Bcl-XL to Induce Apoptosis in Colon Cancer Cells* - Journal of Biological Chemistry

The nuclear function of p53 is required for PUMA-mediated apoptosis induced  by DNA damage | PNAS
The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage | PNAS

The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced  by DNA Damage
The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced by DNA Damage

p53-dependent p21 induction suppresses 17-AAGinduced apoptotic. A,... |  Download Scientific Diagram
p53-dependent p21 induction suppresses 17-AAGinduced apoptotic. A,... | Download Scientific Diagram

Cancers | Free Full-Text | p53-Mediated Tumor Suppression: DNA-Damage  Response and Alternative Mechanisms | HTML
Cancers | Free Full-Text | p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms | HTML

PKR, a p53 target gene, plays a crucial role in the tumor-suppressor  function of p53 | PNAS
PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53 | PNAS

Critical Role of p53 Upregulated Modulator of Apoptosis in Benzyl  Isothiocyanate-Induced Apoptotic Cell Death | PLOS ONE
Critical Role of p53 Upregulated Modulator of Apoptosis in Benzyl Isothiocyanate-Induced Apoptotic Cell Death | PLOS ONE